Dynamics of anti-SARS-CoV-2 IgG antibodies post-COVID-19 in a Brazilian Amazon population

Abstract Background In this study, the prevalence and persistence of anti-SARS-CoV-2 (severe acute respiratory syndrome-coronavirus) IgG was evaluated in volunteers 90 days after COVID-19 (coronavirus disease 2019) diagnosis by correlating response dynamics with clinical conditions, epidemiological characteristics, severity. Methods The study recruited 200 aged 18 years or older both sexes diagnosed COVID-19. Of initially selected, 135 individuals who underwent serological testing for antibodies on first visit to laboratory, were invited return, days, provide a new blood sample second assessment presence antibody. Disease severity longevity symptoms each individual associated profile. Results Among previous test antibody, 125 showed reactivity (92.6%). detectable test, 87 (69.6%) antibody 38 (30.4%) lost evaluation. frequency all reported higher maintained symptoms. Symptom manifestations lasted ?21 group persistent (39.6%) ? 7 nonpersistent (50.0%). length hospital stay supplemental oxygen use response. Conclusions results present show high loss within 3 months Brazilian Amazon.